慢性盐摄入对自发性高血压大鼠（SHRs）大脑皮质毛细血管的影响：一项超微结构研究
Effects of chronic salt intake on the capillaries in the cerebral cortex of spontaneously hypertensive rats (SHRs): an ultrastructural study.
作者信息
Singh D N, Jeria M J
出版信息
Exp Pathol. 1983;23(1):45-52. doi: 10.1016/s0232-1513(83)80040-1.
PMID:6840255
Abstract
Fine structural changes of capillaries in spontaneously hypertensive rats (SHRs) under the influence of 1% NaCl were studied. In SHRs (control), 30 weeks and older, capillaries showed deformed lumina, hypertrophy of endothelial cells and matrical alterations of mitochondria. Deformed capillary lumina, fibrosis in upper stream vessels and swelling of astrocytic processes were observed in the saline-treated SHRs. The significance of these findings is discussed.
摘要
研究了1%氯化钠作用下自发性高血压大鼠（SHRs）毛细血管的超微结构变化。在30周及以上的SHRs（对照组）中，毛细血管显示管腔变形、内皮细胞肥大和线粒体基质改变。在盐水处理的SHRs中观察到毛细血管管腔变形、上游血管纤维化和星形胶质细胞突起肿胀。讨论了这些发现的意义。
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