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在胚胎发育过程中出现一些紊乱的儿童中，1号、9号、16号染色体以及Y染色体上的异染色质区域。

Heterochromatic regions on chromosomes 1, 9, 16, and Y in children with some disturbances occurring during embryo development.

作者信息

Podugolnikova O A, Blumina M G

出版信息

Hum Genet. 1983;63(2):183-8. doi: 10.1007/BF00291542.

DOI:10.1007/BF00291542
PMID:6840762
Abstract

Some reduction of C-segment lengths and their variability on chromosomes 1, 9, 16, and Y was exhibited by children who had had some disturbances at early stages of morphogenesis. The data obtained might suggest a certain activity of the heterochromatic regions during embryo development. Based on this data one may also suppose that reduction of the amount of heterochromatin might affect the normal morphogenetic processes.

摘要

在形态发生早期阶段受到一些干扰的儿童，其1号、9号、16号染色体和Y染色体上的C段长度有所缩短，且变异性增大。所获得的数据可能表明异染色质区域在胚胎发育过程中具有一定活性。基于这些数据，还可以推测异染色质数量的减少可能会影响正常的形态发生过程。

相似文献

1
Heterochromatic regions on chromosomes 1, 9, 16, and Y in children with some disturbances occurring during embryo development.在胚胎发育过程中出现一些紊乱的儿童中，1号、9号、16号染色体以及Y染色体上的异染色质区域。
Hum Genet. 1983;63(2):183-8. doi: 10.1007/BF00291542.
2
[Heterochromatic regions of chromosomes 1, 9, 16 and Y in children with signs of embryonic development disorder].[患有胚胎发育障碍体征儿童的1号、9号、16号染色体及Y染色体的异染色质区域]
Genetika. 1982 Dec;18(12):2052-4.
3
[Human chromosome polymorphism and disordered reproductive function. II. C-variant chromosomes].[人类染色体多态性与生殖功能紊乱。II. C变异染色体]
Genetika. 1979;15(10):1870-9.
4
[Comparative analysis of the polymorphism of the heterochromatic regions of chromosomes 1, 9, 16 and Y in healthy children and children with mild forms of mental retardation].[健康儿童与轻度智力发育迟缓儿童1号、9号、16号染色体及Y染色体异染色质区多态性的比较分析]
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5
Relationship of the variability of the heterochromatic regions of chromosomes 1, 9, 16, and Y to some anthropometric characteristics in children with embryopathies of unknown etiology and in children with Down syndrome.1、9、16号染色体及Y染色体异染色质区变异性与病因不明胚胎病患儿及唐氏综合征患儿某些人体测量特征的关系
Hum Genet. 1984;68(3):254-7. doi: 10.1007/BF00418396.
6
[Heterochromatic regions of human chromosomes 1, 9, 16 and Y and the phenotype].[人类1号、9号、16号染色体以及Y染色体的异染色质区域与表型]
Genetika. 1984 Mar;20(3):496-500.
7
[Polymorphism of the heterochromatic regions of chromosomes 1, 9, 16 and Y and mental retardation].[1、9、16号染色体及Y染色体异染色质区多态性与智力发育迟缓]
Genetika. 1984 Jan;20(1):177-82.
8
[Variability of the heterochromatic regions of human chromosomes 1, 9, 16, and Y].[人类1号、9号、16号和Y染色体异染色质区域的变异性]
Genetika. 1980 Apr;16(4):720-6.
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The quantitative analysis of polymorphism on human chromosomes 1, 9, 16, and Y. III. Study of relationships of C segments' lengths in individual karyotypes.人类1号、9号、16号和Y染色体多态性的定量分析。III. 个体核型中C片段长度关系的研究。
Hum Genet. 1979 Jul 18;49(3):261-8. doi: 10.1007/BF00569345.
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[C-polymorphism of chromosomes 1, 9, 16 and Y in newborn infants of various gestational ages].[不同孕周新生儿1、9、16号染色体及Y染色体的C多态性]
Tsitol Genet. 1986 Mar-Apr;20(2):134-8.

引用本文的文献

1
Relationship of the variability of the heterochromatic regions of chromosomes 1, 9, 16, and Y to some anthropometric characteristics in children with embryopathies of unknown etiology and in children with Down syndrome.1、9、16号染色体及Y染色体异染色质区变异性与病因不明胚胎病患儿及唐氏综合征患儿某些人体测量特征的关系
Hum Genet. 1984;68(3):254-7. doi: 10.1007/BF00418396.
2
C-band length variability and reproductive wastage.C波段长度变异性与生殖损耗
Hum Genet. 1987 Jan;75(1):56-61. doi: 10.1007/BF00273840.
3
Inverted Y chromosome polymorphism in the Gujerati Muslim Indian population of South Africa.

本文引用的文献

1
The quantitative analysis of polymorphism on human chromosomes 1,9,16, and Y. IV. Heterogeneity of a normal population.人类1、9、16号染色体及Y染色体多态性的定量分析。IV. 正常人群的异质性。
Hum Genet. 1980;54(2):163-9. doi: 10.1007/BF00278966.
2
A cloned repeated DNA sequence in human chromosome heteromorphisms.人类染色体异态性中的一个克隆重复DNA序列。
Cytogenet Cell Genet. 1981;29(1):32-9. doi: 10.1159/000131549.
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Differential binding of alkylating fluorochromes in human chromosomes.烷化荧光染料在人类染色体中的差异结合
Hum Genet. 1986 Nov;74(3):223-9. doi: 10.1007/BF00282538.
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Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved "chromatin folding code".人类基因组中串联重复DNA序列块的潜在遗传功能基于一种高度保守的“染色质折叠密码”。
Hum Genet. 1990 Mar;84(4):301-36. doi: 10.1007/BF00196228.
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Evolution of the Simiiformes and the phylogeny of human chromosomes.猿猴亚目动物的进化与人类染色体的系统发育
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Exp Cell Res. 1970 Jun;60(3):315-9. doi: 10.1016/0014-4827(70)90523-9.
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The chromosomal location of human satellite DNA 3.人类卫星DNA 3的染色体定位。
Chromosoma. 1973 Jul 18;42(4):445-51. doi: 10.1007/BF00399411.
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The chromosomal localisation of human satellite DNA I.人类卫星DNA I的染色体定位。
Chromosoma. 1974;49(2):161-71. doi: 10.1007/BF00348888.
6
Staining of some specific regions of human chromosomes, particularly the secondary constriction of No. 9.人类染色体某些特定区域的染色，尤其是9号染色体的次缢痕。
Nat New Biol. 1972 Jul 26;238(82):122-4. doi: 10.1038/newbio238122a0.
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Specific cytological recognition of the heterochromatic segment of number 9 chromosome in man.人类9号染色体异染色质区段的特异性细胞学识别。
Exp Cell Res. 1972 Jul;73(1):239-42. doi: 10.1016/0014-4827(72)90127-9.
8
Cytological mapping of human chromosomes: results obtained with quinacrine fluorescence and the acetic-saline-Giemsa techniques.人类染色体的细胞学图谱：通过喹吖因荧光法和醋酸-盐-吉姆萨技术获得的结果
Chromosoma. 1971;35(3):310-25. doi: 10.1007/BF00326281.
9
Location of satellite and homogeneous DNA sequences on human chromosomes.人类染色体上卫星和同源DNA序列的定位。
Nat New Biol. 1971 Oct 27;233(43):268-71. doi: 10.1038/newbio233268a0.
10
Localization of heterochromatin in human chromosomes.人类染色体中异染色质的定位
Cytogenetics. 1971;10(2):81-6. doi: 10.1159/000130130.