在胚胎发育过程中出现一些紊乱的儿童中，1号、9号、16号染色体以及Y染色体上的异染色质区域。
Heterochromatic regions on chromosomes 1, 9, 16, and Y in children with some disturbances occurring during embryo development.
作者信息
Podugolnikova O A, Blumina M G
出版信息
Hum Genet. 1983;63(2):183-8. doi: 10.1007/BF00291542.
PMID:6840762
Abstract
Some reduction of C-segment lengths and their variability on chromosomes 1, 9, 16, and Y was exhibited by children who had had some disturbances at early stages of morphogenesis. The data obtained might suggest a certain activity of the heterochromatic regions during embryo development. Based on this data one may also suppose that reduction of the amount of heterochromatin might affect the normal morphogenetic processes.
摘要
在形态发生早期阶段受到一些干扰的儿童，其1号、9号、16号染色体和Y染色体上的C段长度有所缩短，且变异性增大。所获得的数据可能表明异染色质区域在胚胎发育过程中具有一定活性。基于这些数据，还可以推测异染色质数量的减少可能会影响正常的形态发生过程。
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