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东印度人Y染色体非荧光区段的种族差异。

Racial variation of a non-fluorescent segment of the Y chromosome in East Indians.

作者信息

Verma R S, Huq A, Dosik H

出版信息

J Med Genet. 1983 Apr;20(2):102-6. doi: 10.1136/jmg.20.2.102.

Abstract

Seventy normal male East Indians were selected to study the length of the fluorescent (f), non-fluorescent (nf), and total length of the Y chromosome by the QFQ technique. The length of the Y chromosome was classified into five groups using subjectively defined criteria, namely, very small, small, average, large, and very large. The frequencies of Y/F indices for these groups were 0.0%, 1.42%, 15.71%, 58.57%, and 24.28%, respectively. The variation in the total length of the Y chromosome was accounted for by variations in the length of the nf as well as the f segments. The mean Y/F, f/F, and nf/F indices for East Indians were 1.20, 0.47, and 0.73, respectively. A longer Y was noted in East Indians primarily owing to an increase in size of the nf segment in comparison to normal black and Caucasian populations. Furthermore, it is emphasised that the definition of 'average' or 'large' Y varies from race to race.

摘要

选取70名正常男性东印度人,采用QFQ技术研究Y染色体的荧光(f)、非荧光(nf)长度及Y染色体总长度。根据主观定义的标准,将Y染色体长度分为五组,即非常小、小、平均、大、非常大。这些组的Y/F指数频率分别为0.0%、1.42%、15.71%、58.57%和24.28%。Y染色体总长度的变化是由nf和f片段长度的变化引起的。东印度人的平均Y/F、f/F和nf/F指数分别为1.20、0.47和0.73。与正常黑人和白种人群体相比,东印度人的Y染色体较长,主要是由于nf片段大小增加。此外,需要强调的是,“平均”或“大”Y的定义因种族而异。

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本文引用的文献

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Higher incidence of small Y chromosome in humans with trisomy 21 (Down syndrome).
Pediatr Res. 1982 Sep;16(9):769-70. doi: 10.1203/00006450-198209000-00012.
8
Chromosomal localization of mouse satellite DNA.小鼠卫星DNA的染色体定位
Science. 1970 Jun 12;168(3937):1356-8. doi: 10.1126/science.168.3937.1356.

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