Verma R S, Dosik H, Scharf T, Lubs H A
J Med Genet. 1978 Aug;15(4):277-81. doi: 10.1136/jmg.15.4.277.
Sixty normal male Caucasians were selected to study the length of the Y chromosome. QFQ banding was performed. Chromosomes 19 and 20 (F) and Y were measured directly from the film. Y/F, f/F, and nf/F indices (f = fluorescent; nf = non-fluorescent segment) were determined. The length of the Y chromosome was classified into 5 groups; very small, small, average, large, and very large with Y/F indices of less than 0.8, 0.81--0.94, 0.95--1.09, 1.1--1.23, and greater than 1.23, respectively. The frequencies of Y/F indices for these groups were 0 (0%), 9 (15.0%), 40 (66.7%), 8 (13.3%), and 3 (5.0%), respectively. The most frequent class was 0.95--1.09 and was defined as the 'average' Y/F index for the human Y chromosome. The variation in the total length of the Y chromosome was accounted for by variations in the length of the non-fluorescent as well as the fluorescent segments. No relation between f and nf segments was observed. The mean Y/F, f/F, and nf/F indices were 1.022, 0.441, and 0.574, respectively.
选取60名正常的男性白种人来研究Y染色体的长度。进行了QFQ显带分析。从胶片上直接测量19号和20号染色体（F）以及Y染色体。测定了Y/F、f/F和nf/F指数（f = 荧光；nf = 非荧光片段）。Y染色体的长度被分为5组：非常小、小、平均、大、非常大，其Y/F指数分别小于0.8、0.81 - 0.94、0.95 - 1.09、1.1 - 1.23以及大于1.23。这些组的Y/F指数频率分别为0（0%）、9（15.0%）、40（66.7%）、8（13.3%）和3（5.0%）。最常见的类别是0.95 - 1.09，被定义为人类Y染色体的“平均”Y/F指数。Y染色体总长度的变化是由非荧光片段以及荧光片段长度的变化所导致的。未观察到f和nf片段之间存在关联。Y/F、f/F和nf/F指数的平均值分别为1.022、0.441和0.574。
