van Rensburg S J, Benadé A S, Rose E F, du Plessis J P
Nutr Cancer. 1983;4(3):206-16. doi: 10.1080/01635588209513759.
Nutritional status indicators were assessed chemically in blood and urine taken from 625 Transkeians drawn from three age-groups in each of two regions: one with a moderate risk for esophageal cancer and one with a very high risk. Aggregate mean values for protein, albumin, vitamin A, and phosphorus were generally acceptable, but many subjects had inadequate (though not necessarily deficient) values for nicotinic acid (74% of subjects), magnesium (60%), vitamin C (55%), carotene (53%), riboflavin (41%), calcium (35%), and zinc (27%). Groups at highest risk for esophageal cancer had markedly lower serum magnesium and carotene concentrations and mildly depressed hemoglobin and hematocrit values, but such findings are not necessarily associated with esophageal cancer etiology. Possible intestinal malabsorption in the populations at highest risk may be associated with the unusually high fiber and phytate intake of the high-risk populations as well as with exposure to necrotizing mycotoxins. Thus, while protein and energy nutriture seem generally adequate, both the high- and moderate-risk populations had high incidences of multiple micronutrient malnutrition.
从两个地区中每个地区的三个年龄组抽取625名特兰斯凯人，采集他们的血液和尿液，对其中的营养状况指标进行化学评估。这两个地区一个食管癌风险中等，另一个风险极高。蛋白质、白蛋白、维生素A和磷的总体平均值一般尚可，但许多受试者的烟酸（74%的受试者）、镁（60%）、维生素C（55%）、胡萝卜素（53%）、核黄素（41%）、钙（35%）和锌（27%）的值不足（尽管不一定缺乏）。食管癌风险最高的组血清镁和胡萝卜素浓度明显较低，血红蛋白和血细胞比容值略有降低，但这些发现不一定与食管癌病因相关。风险最高人群中可能存在的肠道吸收不良，可能与高风险人群异常高的纤维和植酸盐摄入量以及接触坏死性霉菌毒素有关。因此，虽然蛋白质和能量营养似乎总体充足，但高风险和中等风险人群中多种微量营养素营养不良的发生率都很高。
