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低流量濒危脑颅外重建术后的认知改善

Cognitive improvement after extracranial reconstruction for the low flow--endangered brain.

作者信息

Jacobs L A, Ganji S, Shirley J G, Morrell R M, Brinkman S D

出版信息

Surgery. 1983 May;93(5):683-7.

PMID:6845174
Abstract

Twelve patients with multiple occlusive neck vessel lesions were thought to possess low flow-endangered brains. These patients were studied before and after carotid reconstruction with a battery of neuropsychologic tests emphasizing memory and mental agility. A closely matched control group was selected from patients undergoing endarterectomy for hemodynamically insignificant lesions. The patients with low flow-endangered brains showed significantly greater improvements in memory and mental abilities than did the control group. Reconstruction of neck vessels may reverse such global neurologic deficits in carefully selected patients.

摘要

12例患有多发性颈部血管闭塞性病变的患者被认为存在低灌注危及大脑的情况。对这些患者在颈动脉重建术前和术后进行了一系列以记忆和思维敏捷性为重点的神经心理学测试。从因血流动力学意义不大的病变而接受内膜切除术的患者中挑选出一个匹配度很高的对照组。与对照组相比,存在低灌注危及大脑情况的患者在记忆和思维能力方面的改善要显著得多。对精心挑选的患者进行颈部血管重建可能会逆转此类全身性神经功能缺损。

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