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[颈动脉内膜切除术对各种神经心理学参数的影响。一项神经心理学纵向研究]

[Effects of carotid endarterectomy on various neuropsychologic parameters. A neuropsychologic longitudinal study].

作者信息

Lind C, Wimmer A, Magometschnigg H, Ehrmann L, Havelec L, Reichenauer M, Zeiler K

机构信息

Neurologische Universitätsklinik Wien.

出版信息

Langenbecks Arch Chir. 1993;378(6):345-52. doi: 10.1007/BF01876438.

Abstract

Carotid endarterectomy was performed in 25 patients with symptomatic cerebrovascular disease. All patients underwent detailed neuropsychological investigations immediately before surgery, immediately after surgery, and again after a follow-up period of 14 months. Immediately after surgery the flicker fusion frequency was temporarily reduced, indicating an impairment of global cognitive functioning. Postoperatively, verbal attention was found to be improved, particularly in younger patients, in patients with TIA, and in patients with left-sided operation. Finally, visual retention (Benton) was improved at the end of the observation period, especially in older patients and in patients with left-sided operation. Considering the complexity of pathologic brain perfusion, the effects of carotid endarterectomy can only be explained if a multidimensional approach is adopted.

摘要

对25例有症状性脑血管疾病的患者实施了颈动脉内膜切除术。所有患者在手术前、手术后即刻以及14个月的随访期后均接受了详细的神经心理学检查。手术后即刻,闪光融合频率暂时降低,表明整体认知功能受损。术后发现言语注意力有所改善,尤其是在年轻患者、短暂性脑缺血发作(TIA)患者以及接受左侧手术的患者中。最后,在观察期末视觉记忆(本顿测试)有所改善,尤其是在老年患者和接受左侧手术的患者中。考虑到病理性脑灌注的复杂性,只有采用多维度方法才能解释颈动脉内膜切除术的效果。

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