Pechenova T N, Sushkova V V, Solodova E V, Gulyĭ M F
Ukr Biokhim Zh (1978). 1983 Mar-Apr;55(2):146-50.
Protein deficiency and tryptophane load against its background lead to the acid-soluble collagen synthesis in the rat skin. The amino acid composition of the collagen differs from the norm. This is accompanied by changes in the free amino acid pool of blood serum and liver, under tryptophane load the free amino acids pool of the liver increasing twice as high. At the same time protein deficiency increases and tryptophane load decreases the level of tRNA amino acylation with tryptophane in the animal liver. Thus, protein deficiency and tryptophane load against its background cause deep changes in the protein biosynthesis.
蛋白质缺乏及其背景下的色氨酸负荷会导致大鼠皮肤中酸溶性胶原蛋白的合成。胶原蛋白的氨基酸组成与正常情况不同。这伴随着血清和肝脏游离氨基酸池的变化，在色氨酸负荷下，肝脏的游离氨基酸池增加了两倍。同时，蛋白质缺乏会增加，而色氨酸负荷会降低动物肝脏中色氨酸对tRNA的氨酰化水平。因此，蛋白质缺乏及其背景下的色氨酸负荷会导致蛋白质生物合成发生深刻变化。
