Carlson L A, Holmquist L
Acta Med Scand. 1983;213(3):177-82. doi: 10.1111/j.0954-6820.1983.tb03713.x.
Serum high density lipoproteins (HDL) were isolated by preparative ultracentrifugation from two patients with fish eye disease (FED). Compared to HDL from control subjects the HDL particles of FED were characterized by their abnormally small size and a relative enrichment with polar lipids. No qualitative abnormalities of the HDL apolipoproteins were revealed upon polyacrylamide disc gel electrophoresis or isoelectric focusing. The plasma pool of apolipoprotein A was reduced by 90%.
通过制备性超速离心从两名鱼眼病（FED）患者中分离出血清高密度脂蛋白（HDL）。与对照组受试者的HDL相比，FED的HDL颗粒具有异常小的尺寸和相对富含极性脂质的特征。在聚丙烯酰胺圆盘凝胶电泳或等电聚焦时未发现HDL载脂蛋白有定性异常。载脂蛋白A的血浆池减少了90%。
