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I期子宫内膜腺癌:835例患者的治疗结果

Stage I endometrial adenocarcinoma: treatment results in 835 patients.

作者信息

Lotocki R J, Copeland L J, DePetrillo A D, Muirhead W

出版信息

Am J Obstet Gynecol. 1983 May 15;146(2):141-5. doi: 10.1016/0002-9378(83)91042-6.

DOI:10.1016/0002-9378(83)91042-6
PMID:6846429
Abstract

A 16-year review of 835 patients with Stage I adenocarcinoma of the uterus revealed histologic grade and depth of myometrial invasion to be salient prognostic factors. Sixteen percent of patients developed recurrent disease and despite aggressive treatment, only 10% of these survived. Preoperative or postoperative radium decreased the incidence of vault recurrence.

摘要

一项对835例子宫I期腺癌患者进行的为期16年的回顾性研究显示,组织学分级和肌层浸润深度是显著的预后因素。16%的患者出现复发性疾病,尽管进行了积极治疗,但这些患者中只有10%存活下来。术前或术后镭疗可降低阴道残端复发的发生率。

相似文献

1
Stage I endometrial adenocarcinoma: treatment results in 835 patients.I期子宫内膜腺癌:835例患者的治疗结果
Am J Obstet Gynecol. 1983 May 15;146(2):141-5. doi: 10.1016/0002-9378(83)91042-6.
2
Adenocarcinoma of the endometrium stage I. Treatment, survival and recurrence.子宫内膜癌I期。治疗、生存及复发情况。
Acta Obstet Gynecol Scand. 1984;63(1):51-5. doi: 10.3109/00016348409156273.
3
Endometrial carcinoma: stage I. A retrospective analysis of 262 patients.
Obstet Gynecol. 1982 Aug;60(2):225-31.
4
Risk factors and recurrent patterns in Stage I endometrial cancer.I期子宫内膜癌的危险因素及复发模式。
Am J Obstet Gynecol. 1985 Apr 15;151(8):1009-15. doi: 10.1016/0002-9378(85)90371-0.
5
Clinical stage I and II endometrial carcinoma treated with surgery and/or radiation therapy: analysis of prognostic and treatment-related factors.
Gynecol Oncol. 1989 Jun;33(3):290-5. doi: 10.1016/0090-8258(89)90514-3.
6
Evaluation of unfavorable histologic subtypes in endometrial adenocarcinoma.子宫内膜腺癌中不良组织学亚型的评估
Am J Obstet Gynecol. 1990 Feb;162(2):418-23; discussion 423-6. doi: 10.1016/0002-9378(90)90399-r.
7
Analysis of residual disease following preoperative radiotherapy versus initial surgery in endometrial carcinoma.
Int J Radiat Oncol Biol Phys. 1982 Feb;8(2):213-8. doi: 10.1016/0360-3016(82)90516-8.
8
Endometrial carcinoma stage I--comparison of two different treatment regimes--evaluation of risk factors and its influence on prognosis; suggested step by step treatment protocol.子宫内膜癌I期——两种不同治疗方案的比较——风险因素评估及其对预后的影响;建议的逐步治疗方案
Gynecol Oncol. 1985 Nov;22(3):294-301. doi: 10.1016/0090-8258(85)90043-5.
9
Recurrent adenocarcinoma of the endometrium: a clinical and histopathological study of 379 patients.复发性子宫内膜腺癌:379例患者的临床与组织病理学研究
Gynecol Oncol. 1984 Jan;17(1):85-103. doi: 10.1016/0090-8258(84)90063-5.
10
Treatment of stage II endometrial carcinoma.
Gynecol Oncol. 1989 May;33(2):204-8. doi: 10.1016/0090-8258(89)90553-2.

引用本文的文献

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The Potential Value of Ki-67 in Prognostic Classification in Early Low-Risk Endometrial Cancer.Ki-67 在早期低危型子宫内膜癌预后分类中的潜在价值。
Cancer Control. 2023 Jan-Dec;30:10732748231206929. doi: 10.1177/10732748231206929.
2
Effect of Pelvic Lymphadenectomy on Survival in Patients with Low-Risk Early-Stage Endometrial Cancer Diagnosed Intraoperatively Using Frozen Tissue Sections: A Retrospective Analysis.盆腔淋巴结清扫术对术中采用冰冻组织切片诊断的低风险早期子宫内膜癌患者生存的影响:一项回顾性分析
Cancer Manag Res. 2020 Oct 29;12:10715-10723. doi: 10.2147/CMAR.S274992. eCollection 2020.
3
Small interfering RNA-mediated knockdown of Twist attenuates the aggressive phenotypes of human endometrial carcinoma Ishikawa cells.
小干扰RNA介导的Twist基因敲低可减弱人子宫内膜癌Ishikawa细胞的侵袭性表型。
Exp Ther Med. 2017 Dec;14(6):5647-5651. doi: 10.3892/etm.2017.5214. Epub 2017 Sep 27.
4
MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis.MIIP通过重塑Rac1介导的细胞骨架结构来抑制子宫内膜癌转移。
J Hematol Oncol. 2016 Oct 19;9(1):112. doi: 10.1186/s13045-016-0342-6.
5
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.微小RNA-505通过靶向转化生长因子-α发挥子宫内膜癌抑癌基因的作用。
Mol Cancer. 2016 Feb 2;15:11. doi: 10.1186/s12943-016-0496-4.
6
Uterine smooth muscle cells increase invasive ability of endometrial carcinoma cells through tumor-stromal interaction.子宫平滑肌细胞通过肿瘤-基质相互作用增强子宫内膜癌细胞的侵袭能力。
Clin Exp Metastasis. 2007;24(6):423-9. doi: 10.1007/s10585-007-9079-5. Epub 2007 Jun 21.
7
Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer.吲哚胺2,3-双加氧酶是子宫内膜癌一种新的预后指标。
Br J Cancer. 2006 Dec 4;95(11):1555-61. doi: 10.1038/sj.bjc.6603477. Epub 2006 Nov 21.
8
Expression of the hyaluronan receptor RHAMM in endometrial carcinomas suggests a role in tumour progression and metastasis.透明质酸受体RHAMM在子宫内膜癌中的表达表明其在肿瘤进展和转移中发挥作用。
J Cancer Res Clin Oncol. 2003 Mar;129(3):161-4. doi: 10.1007/s00432-003-0415-0. Epub 2003 Feb 20.
9
Low levels of cathepsin D are associated with a poor prognosis in endometrial cancer.组织蛋白酶D水平低与子宫内膜癌的不良预后相关。
Br J Cancer. 1999 Feb;79(3-4):570-6. doi: 10.1038/sj.bjc.6690090.
10
Serum and tissue measurements of CA72-4 in patients with endometrial carcinoma.子宫内膜癌患者血清及组织中CA72-4的测定
J Clin Pathol. 1996 Dec;49(12):967-70. doi: 10.1136/jcp.49.12.967.