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健康男性的肺功能测定:与吸烟及轻微症状的相关性

Spirometry in healthy men: a correlation with smoking and with mild symptoms.

作者信息

Prieto F, English M J, Cochrane G M, Clark T J, Rigden B G

出版信息

Thorax. 1978 Jun;33(3):322-7. doi: 10.1136/thx.33.3.322.

Abstract

Symptoms, smoking history, and variates taken from the forced expiratory manoeuvre were studied in a group of 271 healthy men attending a mass radiography unit. It was found that correlation of the forced expiratory ratio (FEV1/FVC) with the presence of mild or moderate respiratory symptoms was at least as satisfactory as that of technically more complicated measurements such as MEF50 and MEF75. In asymptomatic individuals those differences associated with smoking were the same for FEV1/FVC as for MEF75. Asymptomatic abnormalities of lung function were not observed. Simple measurements such as FEV1/FVC can therefore provide as much information from a forced expiratory manoeuvre to screen for early airways obstruction as MEF50 and MEF75.

摘要

对一组前往大规模X光摄影单位的271名健康男性进行了症状、吸烟史以及用力呼气动作所采集变量的研究。结果发现,用力呼气比率(FEV1/FVC)与轻度或中度呼吸道症状之间的相关性,至少与技术上更为复杂的测量指标(如MEF50和MEF75)一样令人满意。在无症状个体中,FEV1/FVC与吸烟相关的差异与MEF75相同。未观察到无症状的肺功能异常。因此,诸如FEV1/FVC这样的简单测量指标,在用力呼气动作中能够提供与MEF50和MEF75一样多的信息,用于筛查早期气道阻塞。

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本文引用的文献

2
Mechanics of airflow in health and in emphysema.健康与肺气肿状态下的气流动力学
J Clin Invest. 1951 Nov;30(11):1175-90. doi: 10.1172/JCI102537.
6
The expiratory spirogram.呼气肺量图。
Am Rev Respir Dis. 1961 Jun;83:842-55. doi: 10.1164/arrd.1961.83.6.842.
10
Maximal midexpiratory flow.最大呼气中期流速
Am Rev Tuberc. 1955 Dec;72(6):783-800. doi: 10.1164/artpd.1955.72.6.783.

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