Newman A N, Rice D H, Ossoff R H, Sisson G A
Arch Otolaryngol. 1983 May;109(5):302-4. doi: 10.1001/archotol.1983.00800190024006.
Squamous cell carcinoma of the tongue in young people is a rare disease. The usual causal agents associated with this disease in older patients may not be operative in this younger age group or may involve a greatly reduced latency. Failure to perform a biopsy of tongue lesions in young patients often leads to late diagnosis. The prognosis is similar, stage for stage, as for older patients. Thirteen cases of squamous cell carcinoma of the tongue occurred in patients younger than 30 years of age. Their clinical appearance, stage and histologic state, treatment, and survival are discussed. A high index of suspicion leading to early diagnosis and systematic adequate treatment are needed to alter the unfavorable prognosis of this lesion.
年轻人舌鳞状细胞癌是一种罕见疾病。在老年患者中与该疾病相关的常见致病因素在这个较年轻年龄组中可能不起作用，或者可能涉及潜伏期大大缩短。年轻患者舌部病变未进行活检常常导致诊断延迟。逐期来看，其预后与老年患者相似。13例舌鳞状细胞癌发生在30岁以下患者中。本文讨论了这些患者的临床表现、分期、组织学状态、治疗及生存情况。需要高度的怀疑指数以实现早期诊断，并进行系统充分的治疗，从而改变这种病变的不良预后。
