Frolov A K, Chaĭkovskaia T L, Frolov V K
Tsitol Genet. 1978 Jan-Feb;12(1):44-9.
After immunization with vaccinia virus an increase in frequency of aneuploids and secondary chromosomal constrictions is observed in adult mice. Moreover, an increased frequency of chromosomal aberrations was demonstrated. The increase in the number of secondary chromosomal constrictions indicates an activation of nucleolar-organizing regions.
用痘苗病毒免疫成年小鼠后,观察到非整倍体和次级染色体缢痕的频率增加。此外,还证实了染色体畸变频率的增加。次级染色体缢痕数量的增加表明核仁组织区被激活。