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[野生小鼠与实验小鼠杂交的细胞遗传学后果]

[Cytogenetic consequences of hybridization between wild and laboratory mice].

作者信息

Borodin P M, Gorlov I P

出版信息

Genetika. 1986 May;22(5):855-60.

PMID:3732798
Abstract

Wild mice from the aboriginal population were crossed with the laboratory C57BL/6 mice. F1 hybrids were backcrossed with both parents. Significant increase of recombination frequency in the AY-Ra region of the 2nd chromosome (from 22.0 to 33.1 cM), of the frequency of occurrence of X-Y univalents (up to 54.6%) and of autosomal univalents (up to 9.1%) was found in the F1. In backcrosses all these induces decreased gradually.

摘要

将来自原始种群的野生小鼠与实验室C57BL/6小鼠进行杂交。F1代杂种与双亲进行回交。在F1代中发现,第二条染色体的AY-Ra区域的重组频率显著增加(从22.0厘摩增加到33.1厘摩),X-Y单价体的出现频率(高达54.6%)和常染色体单价体的出现频率(高达9.1%)也显著增加。在回交中,所有这些诱导因素逐渐减少。

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