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[不同年龄家兔长期用同源心脏抗原免疫对血脂及脂蛋白含量的影响]

[Effect of long-term immunization of rabbits of different ages with homologous heart antigen on blood lipid and lipoprotein content].

作者信息

Zaĭchenko A P, Chaialo P P

出版信息

Biull Eksp Biol Med. 1983 May;95(5):57-9.

PMID:6850091
Abstract

The data are provided on the content of lipid and lipoproteins in the blood of young and old rabbits during long-term immunization with homologous heart antigen (once a week for 2.5 months). Two weeks after the beginning of the experiment the blood of immunized animals showed cardiac antibodies whose content rose, especially in young animals, in the course of the experiment. The content of immune complexes circulating in the blood also increased, with this increase being more pronounced in old rabbits. During immunization, the blood levels of lipoproteins total cholesterol, and triacylglycerins in old animals increased earlier and more intensely.

摘要

提供了年轻和老年兔子在长期用同源心脏抗原免疫(每周一次,持续2.5个月)期间血液中脂质和脂蛋白含量的数据。实验开始两周后,免疫动物的血液中出现了心脏抗体,其含量在实验过程中上升,尤其是在年轻动物中。血液中循环免疫复合物的含量也增加了,这种增加在老年兔子中更为明显。在免疫过程中,老年动物血液中脂蛋白、总胆固醇和三酰甘油的水平升高得更早且更强烈。

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Biull Eksp Biol Med. 1983 May;95(5):57-9.
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