Laurman W
Med Pr. 1980;31(3):171-6.
In rabbits chronically intoxicated with CS2, the lipids and lipoproteins concentration in the blood serum and cholesterol content in the serum lipoproteins and arterial wall were evaluated. It has been shown, that 6 months' exposure to CS2 at the concentration of 0,5-0,6 mg/l resulted in: (1) an increase in total and free cholesterol, cholesterol esters, triglycerides and phospholipides content in serum; (2) a relative increase in serum VLDL and LDL content and decrease in HDL fraction content; (3) a significant increased in cholesterol concentration in LDL and a slight one in VLDL and LDL fractions. No changes in the concentration of lipids in the aorta wall of CS2-intoxicated animals were observed.
对长期吸入二硫化碳（CS2）的家兔，评估其血清中的脂质和脂蛋白浓度以及血清脂蛋白和动脉壁中的胆固醇含量。结果显示，家兔在浓度为0.5 - 0.6毫克/升的CS2环境中暴露6个月会导致：（1）血清中总胆固醇、游离胆固醇、胆固醇酯、甘油三酯和磷脂含量增加；（2）血清极低密度脂蛋白（VLDL）和低密度脂蛋白（LDL）含量相对增加，高密度脂蛋白（HDL）含量降低；（3）低密度脂蛋白中的胆固醇浓度显著增加，极低密度脂蛋白和低密度脂蛋白部分略有增加。未观察到CS2中毒动物主动脉壁脂质浓度有变化。
