Fleig I, Rieth H, Stocker W G, Thiess A M
Ecotoxicol Environ Saf. 1983 Feb;7(1):106-10. doi: 10.1016/0147-6513(83)90054-4.
Chromosome analyses were undertaken on 14 workers exposed to cadmium and the results were compared with a corresponding control group. All probands have been employed for many years in cadmium pigment and stabilizer production plants (between 6 and 25 years). The results of the clinical investigations were, for the most part, unspecific, although at the same time some parameters were above the normal (transaminase, beta 2-microglobulin deposit in the urine, as well as cadmium in the blood and urine). The chromosome analyses were undertaken on the lymphocytes of the peripheral blood with the aid of the so-called "micromethod." Metaphases, 150 per person, were analyzed. The statistical evaluation was made according to the Fisher-Yates test. The chromosome aberration rate of the group investigated was not higher than that of the control group, inclusive and exclusive of gaps.
对14名接触镉的工人进行了染色体分析，并将结果与相应的对照组进行了比较。所有先证者均在镉颜料和稳定剂生产厂工作多年（6至25年）。临床调查结果大多无特异性，尽管同时一些参数高于正常水平（转氨酶、尿中β2-微球蛋白沉积以及血液和尿液中的镉）。借助所谓的“微量法”对外周血淋巴细胞进行染色体分析。每人分析150个中期相。根据费希尔-耶茨检验进行统计评估。所调查组的染色体畸变率不高于对照组，包括和不包括裂隙。
