Werbin N
Eur Surg Res. 1983;15(2):73-8. doi: 10.1159/000128336.
The effect of splenectomy on wound healing has been studied in standard laparotomy wounds in rats. Significant differences in wound histology, fibroblastic labelling indices, bursting pressure, and IgM levels were found between chronically asplenic rats and controls. Autotransplantation of the spleen conferred some increase to wound strength. Acute asplenic rats have not demonstrated the same changes. It is concluded that the spleen influences wound healing probably through a fibroblastic stimulating mechanism.
已在大鼠的标准剖腹手术伤口中研究了脾切除术对伤口愈合的影响。在慢性脾切除大鼠和对照组之间，发现伤口组织学、成纤维细胞标记指数、破裂压力和IgM水平存在显著差异。脾脏自体移植使伤口强度有所增加。急性脾切除大鼠未表现出相同的变化。结论是，脾脏可能通过成纤维细胞刺激机制影响伤口愈合。
