Synthesis and biological assays of peptides from a tuberculin-active protein.
作者信息
Savrda J
出版信息
Infect Immun. 1983 Jun;40(3):1163-9. doi: 10.1128/iai.40.3.1163-1169.1983.
Abstract
The octapeptide Asp-Gly-Gly-Ser-Glu-Ser-Glu-Gly and the hexadecapeptide Asp-Gly-Gly-Ser-Glu-Ser-Glu-Gly-Lys-Asn-Gly-Ser-Gln-Met-Arg-Leu, part of a tuberculin-active intracellular mycobacterial protein, were synthesized. The synthetic peptides were shown to possess tuberculin activity by their ability to elicit a delayed-type allergic reaction in skin tests on Mycobacterium tuberculosis-sensitized guinea pigs. Purified protein derivative, the complex mixture of proteins of unknown composition which are excreted into the culture medium by M. tuberculosis and which is in wide use as a tuberculin-active preparation, was shown to cross-react weakly in the radioimmunoassays with the synthetic octapeptide when the 125I-labeled octapeptide and an anti-octapeptide antiserum were used.
摘要
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1
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2
Electrophoretic mobilities of peptides on paper and their use in the determination of amide groups.肽在纸上的电泳迁移率及其在酰胺基团测定中的应用。
Nature. 1966 Aug 6;211(5049):591-3. doi: 10.1038/211591a0.
3
[On the synthesis of glucagon. X. Preparation of sequence 22-29].
Chem Ber. 1966 Jan;99(1):110-20. doi: 10.1002/cber.19660990119.
4
The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent.通过与含¹²⁵I的酰化剂结合将蛋白质标记至高比放射性。
Biochem J. 1973 Jul;133(3):529-39. doi: 10.1042/bj1330529.
5
Boron tris(trifluoroacetate) for removal of protecting groups in peptide chemistry.用于肽化学中去除保护基团的三（三氟乙酸）硼。
Angew Chem Int Ed Engl. 1973 Feb;12(2):147-8. doi: 10.1002/anie.197301471.
6
Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives.细菌肽聚糖衍生物佐剂活性的最小结构要求。
Biochem Biophys Res Commun. 1974 Aug 19;59(4):1317-25. doi: 10.1016/0006-291x(74)90458-6.
7
[Basic peptides in bee venom, II. Synthesis of two pentapeptides from the sequence of the mast-cell-degrading peptide (author's transl)].
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8
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