胎儿及成人人类乙酰胆碱受体与重症肌无力患者血清的相互作用。
Interaction of foetal and adult human acetylcholine receptors with serum from patients with myasthenia gravis.
作者信息
Lotwick H, Harrison R, Lunt G, Behan P
出版信息
J Neuroimmunol. 1983 Jun;4(3):167-74. doi: 10.1016/0165-5728(83)90033-4.
PMID:6853696
Abstract
Acetylcholine receptors were partially purified from foetal and adult human muscle and their binding to myasthenic serum was compared. No significant differences between the binding characteristics of the two receptor types were detected; indicating the absence, at least in 14-22-week-old foetuses of antigenic sites unique to foetal receptor and recognised by myasthenic sera.
摘要
从胎儿和成人的肌肉中部分纯化了乙酰胆碱受体，并比较了它们与重症肌无力血清的结合情况。未检测到两种受体类型在结合特性上有显著差异；这表明至少在14 - 22周龄的胎儿中不存在胎儿受体特有的、能被重症肌无力血清识别的抗原位点。
Zotero 插件