Nanji A A, Reddy S
J Clin Pathol. 1983 Jun;36(6):716-8. doi: 10.1136/jcp.36.6.716.
In a study of apparently healthy males, we noted a correlation between serum albumin and high density lipoprotein cholesterol (HDL-C) (r = 0.32, p less than 0.001). We then correlated the total cholesterol:albumin ratio (TC:Alb) with the TC:HDL-C ratio (r = 0.89, p less than 0.001). We used the TC:Alb ratio to determine whether this was better than TC by itself in predicting whether an individual had a TC:HDL-C ratio of less than or greater than or equal to 5. The ratio performed better than TC and correctly classified 89% of individuals (66% with TC) (p less than 0.001). Since measurements of TC and Alb are routinely available on multichannel analysers, use of this ratio would provide a less expensive alternative to HDL-C measurement.
在一项针对表面健康男性的研究中，我们发现血清白蛋白与高密度脂蛋白胆固醇（HDL-C）之间存在相关性（r = 0.32，p < 0.001）。然后，我们将总胆固醇与白蛋白比值（TC:Alb）与总胆固醇与高密度脂蛋白胆固醇比值（TC:HDL-C）进行了相关性分析（r = 0.89，p < 0.001）。我们使用TC:Alb比值来确定其在预测个体的TC:HDL-C比值小于或大于或等于5方面是否比单独的总胆固醇更好。该比值的表现优于总胆固醇，能够正确分类89%的个体（总胆固醇为66%）（p < 0.001）。由于总胆固醇和白蛋白的测量在多通道分析仪上常规可用，使用该比值将提供一种比测量HDL-C成本更低的替代方法。
