Holden R A, Ostfeld A M, Freeman D H, Hellenbrand K G, D'Atri D A
JAMA. 1983 Jul 15;250(3):365-9.
With an index for dietary salt use designed to provide a semiquantitative estimate of salt intake, we have found that in a sample representative of the 2.1 million adults in Connecticut, the mean BP of those at the 90th percentile or higher of salt intake differs by a quantitatively insignificant amount from the mean BP of those at the tenth percentile or lower of salt intake. When we examined the obese (body mass index, 90th percentile or higher) separately, similar results were obtained. These findings indicate that it is unlikely dietary salt intake has a clinically significant effect on BP in the majority of individuals in a large defined population, but do not exclude the possibility of a clinically significant effect in a small subgroup of salt-sensitive individuals.
通过一个旨在对盐摄入量进行半定量估计的膳食盐使用指数，我们发现，在一个代表康涅狄格州210万成年人的样本中，盐摄入量处于第90百分位数或更高水平者的平均血压与盐摄入量处于第10百分位数或更低水平者的平均血压在数量上差异不显著。当我们分别检查肥胖者（体重指数处于第90百分位数或更高水平）时，也得到了类似的结果。这些发现表明，在一个大型特定人群中的大多数个体中，膳食盐摄入量对血压不太可能产生具有临床意义的影响，但并不排除在一小部分盐敏感个体中产生具有临床意义影响的可能性。
