Ghanadian R, Williams G, Coleman A P
Prog Clin Biol Res. 1982;100:245-54.
The presence of androgen and oestrogen receptors in normal and malignant human kidneys is reported. Characterization of these receptors was performed by glycerol gradient centrifugation and isoelectric focusing. Androgen receptors were detected in 40% of the tissues and its concentration was higher in the malignant kidneys. Oestrogen receptors were demonstrable in 8 out of 9 tumours, but only one out of 7 normal kidneys. The level of this receptor was extremely low.
据报道，在正常和恶性人肾组织中存在雄激素和雌激素受体。通过甘油梯度离心和等电聚焦对这些受体进行了表征。在40%的组织中检测到雄激素受体，其在恶性肾组织中的浓度更高。在9个肿瘤中有8个可检测到雌激素受体，但在7个正常肾组织中只有1个可检测到。该受体水平极低。
