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人乳中的鲨烯醇。

Desmosterol in human milk.

作者信息

Clark R M, Fey M B, Jensen R G, Hill D W

出版信息

Lipids. 1983 Mar;18(3):264-6. doi: 10.1007/BF02534559.

DOI:10.1007/BF02534559
PMID:6855485
Abstract

Milk samples were collected from mothers at 2, 6, 12 and 16 weeks postpartum. Desmosterol was found to be present in all the milk samples. Identification of desmosterol was based on retention times with two gas liquid chromatography (GLC) columns and verified by GC-mass spectrometry. The concentration of desmosterol in breast milk increased significantly (P less than .05) from 0.6 mg/100 ml at 2 weeks to 1.3 mg/100 ml at 16 weeks postpartum. Desmosterol was not significantly correlated with total lipid, total cholesterol or free cholesterol in the milk.

摘要

在产后2周、6周、12周和16周从母亲处采集乳汁样本。发现所有乳汁样本中均存在胆甾烯醇。胆甾烯醇的鉴定基于在两根气液色谱(GLC)柱上的保留时间,并通过气相色谱-质谱联用仪进行验证。母乳中胆甾烯醇的浓度从产后2周时的0.6毫克/100毫升显著增加(P<0.05)至产后16周时的1.3毫克/100毫升。胆甾烯醇与乳汁中的总脂质、总胆固醇或游离胆固醇无显著相关性。

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本文引用的文献

1
Changes in the lipids of human milk from 2 to 16 weeks postpartum.
J Pediatr Gastroenterol Nutr. 1982;1(3):311-5. doi: 10.1097/00005176-198201030-00006.
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Composition of the lipids in human milk: a review.人乳中脂质的组成:综述
Lipids. 1980 May;15(5):345-55. doi: 10.1007/BF02533550.
3
Reactivity of key metabolic sterols in standard colorimetric assays for cholesterol.胆固醇标准比色测定中关键代谢固醇的反应性。
Lipids. 1982 Jan;17(1):46-9. doi: 10.1007/BF02535121.
美国母乳的营养成分:当前认知、挑战及研究需求
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The Smith-Lemli-Opitz syndrome.史密斯-勒米-奥皮茨综合征
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5
Silver ion high pressure liquid chromatography provides unprecedented separation of sterols: application to the enzymatic formation of cholesta-5,8-dien-3 beta-ol.银离子高效液相色谱法实现了甾醇前所未有的分离:应用于胆甾-5,8-二烯-3β-醇的酶促合成。
Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11603-8. doi: 10.1073/pnas.93.21.11603.
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Lipids of human milk and infant formulas: a review.
Am J Clin Nutr. 1978 Jun;31(6):990-1016. doi: 10.1093/ajcn/31.6.990.