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[减敏疗法对儿童支气管哮喘支气管组胺反应性的影响]

[The effect of hyposensitization in bronchial asthma of childhood with regard to the histamine reactivity of the bronchial tract].

作者信息

Bauer P, Schwager R

出版信息

Monatsschr Kinderheilkd. 1983 Mar;131(3):140-4.

PMID:6855780
Abstract

86 children with asthma were re-examined after receiving hyposensitization for a period of two years. A measurable decrease in the bronchial hypersensitivity was recorded in 40 patients. The group of children suffering from asthma during the grass pollen season showed a more favourable result, compared to patients with perennial asthma. 16 patients demonstrated an unchanged histamine response. The bronchial hypersensitivity was increased in 30 patients. Personally interviewed, 39.5% indicated a notable improvement, 55.8% no change and 4.7% a deterioration. There was no significant change in the bronchial hypersensitivity to histamine following hyposensitization. Only in some cases there was a correlation between the results of bronchial hypersensitivity and the subjective changes.

摘要

86名哮喘患儿在接受了为期两年的减敏治疗后接受了复查。40名患者的支气管超敏反应出现了可测量的下降。与常年性哮喘患者相比,在草花粉季节患哮喘的儿童组显示出更有利的结果。16名患者的组胺反应未发生变化。30名患者的支气管超敏反应增强。在个人访谈中,39.5%的人表示有显著改善,55.8%的人表示无变化,4.7%的人表示病情恶化。减敏治疗后,支气管对组胺的超敏反应没有显著变化。只有在某些情况下,支气管超敏反应的结果与主观变化之间存在相关性。

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