[The effect of hyposensitization in bronchial asthma of childhood with regard to the histamine reactivity of the bronchial tract].

86 children with asthma were re-examined after receiving hyposensitization for a period of two years. A measurable decrease in the bronchial hypersensitivity was recorded in 40 patients. The group of children suffering from asthma during the grass pollen season showed a more favourable result, compared to patients with perennial asthma. 16 patients demonstrated an unchanged histamine response. The bronchial hypersensitivity was increased in 30 patients. Personally interviewed, 39.5% indicated a notable improvement, 55.8% no change and 4.7% a deterioration. There was no significant change in the bronchial hypersensitivity to histamine following hyposensitization. Only in some cases there was a correlation between the results of bronchial hypersensitivity and the subjective changes.