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新鲜组织和固定组织的核磁共振特征:时间流逝的影响

Nuclear magnetic resonance characteristics of fresh and fixed tissue: the effect of elapsed time.

作者信息

Thickman D I, Kundel H L, Wolf G

出版信息

Radiology. 1983 Jul;148(1):183-5. doi: 10.1148/radiology.148.1.6856832.

DOI:10.1148/radiology.148.1.6856832
PMID:6856832
Abstract

The nuclear magnetic resonance relaxation times T1 and T2 of liver and spleen from freshly euthanized rats were measured over 48 hours for samples treated with normal saline, fixed with 70% ethanol, neutral buffered formalin, or 10% formalin, or left untreated. The initial values of T1 and T2 for both tissues agreed with previous determinations. For untreated tissues of both liver and spleen, T1 was stable for 6 hours and T2 was stable for 48 hours. For fixed tissues, T1 was stable for 0.5 hours, but T2 changed in 0.5 hours.

摘要

对刚安乐死的大鼠的肝脏和脾脏进行核磁共振弛豫时间T1和T2的测量,测量时间为48小时,样本分别用生理盐水处理、用70%乙醇固定、用中性缓冲甲醛或10%甲醛固定,或不做处理。两种组织的T1和T2初始值与先前测定结果一致。对于肝脏和脾脏的未处理组织,T1在6小时内保持稳定,T2在48小时内保持稳定。对于固定组织,T1在0.5小时内保持稳定,但T2在0.5小时内发生变化。

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