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[正常人血细胞蛋白质和白血病中的多胺]

[Polyamines in normal human blood cell proteins and in leukosis].

作者信息

Blinov M N, Luganova I S, Vladimirova A D

出版信息

Vopr Med Khim. 1983 Mar-Apr;29(2):124-6.

PMID:6858029
Abstract

Content of putrescine, spermidine and spermine was estimated in leukocytes of healthy persons and of patients with various forms of leukoses. Spermine was the main component of the polyamine fraction in leukocytes; only small amount of putrescine was found. In leukoses, as the cell population rejuvenated, content of polyamines increased with elevation in the ratio spermidine/spermine approaching the maximal value in blast cells of blood from patients with acute leukosis.

摘要

对健康人和患有各种白血病的患者白细胞中的腐胺、亚精胺和精胺含量进行了估算。精胺是白细胞中多胺组分的主要成分;仅发现少量腐胺。在白血病中,随着细胞群体年轻化,多胺含量增加,亚精胺/精胺比值升高,接近急性白血病患者血液原始细胞中的最大值。

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