Stanulla H
Zentralbl Allg Pathol. 1983;127(1-2):97-103.
Five autoptically proven cases with mycotic prosthetic valve endocarditis are reported with special reference to morphologic findings. The clinical signs in such patients manifest in the early post-operative phase and are accompanied with a high mortality rate. At autopsy, there were in all cases thrombotic vegetations upon the prosthetic valves which often caused severe arterial and cerebral embolic events. Histologically, fungi are demonstrable within the thrombotic material without any difficulties, and after embolectomy intra vitam, too. In addition to pathological aspects, the author briefly summarizes the most important symptoms of this affection, its arduous diagnostic management, its possible mode of infection, and its treatment.
本文报告了5例经尸检证实的真菌性人工瓣膜心内膜炎病例,并特别提及形态学发现。此类患者的临床症状在术后早期出现,且死亡率很高。尸检时,所有病例的人工瓣膜上均有血栓性赘生物,常导致严重的动脉和脑栓塞事件。组织学上,在血栓物质中很容易发现真菌,在活体栓子切除术后也能发现。除了病理学方面,作者还简要总结了这种疾病的最重要症状、艰难的诊断处理、可能的感染方式及其治疗方法。