Noto R, Alicata R, Sfogliano L, Neri S, Bifarella M
Acta Diabetol Lat. 1983 Jan-Mar;20(1):81-5. doi: 10.1007/BF02629133.
In diabetics, even in those without complications and/or alterations of lipid metabolism, higher levels of cupremia were found than in the controls; these increased levels were not correlated with the duration of the disease and the cupremia was more evident in the older patients and in those with complications. However, the increases were not dissimilar from those found in non-diabetic arteriosclerosis. Our findings favor the hypothesis that after some years and by affecting fatty acid metabolism, higher levels of cupremia enhance the appearance of diabetic vasculopathy.
在糖尿病患者中,即使是那些没有并发症和/或脂质代谢改变的患者,其血铜水平也高于对照组;这些升高的水平与疾病持续时间无关,且血铜水平在老年患者和有并发症的患者中更为明显。然而,这些升高与非糖尿病性动脉硬化患者中发现的升高并无差异。我们的研究结果支持这样一种假说,即经过数年并通过影响脂肪酸代谢,较高的血铜水平会促进糖尿病血管病变的出现。