Weisman L E, Merenstein G B, Digirol M, Collins J, Frank G, Hudgins C
Am J Dis Child. 1983 Jul;137(7):666-8. doi: 10.1001/archpedi.1983.02140330050013.
Delayed passage of meconium has been associated with hyperbilirubinemia. To determine if early evacuation of meconium is effective in reducing total serum bilirubin level, 84 term healthy neonates were randomly assigned to a suppository group or a nonsuppository group. Use of suppositories resulted in earlier evacuation of meconium as measured by the appearance of transitional stool. No significant effect was noted, however, on total serum bilirubin levels in the first three days of life. Routine use of suppositories to decrease total serum bilirubin level cannot be recommended for term healthy neonates.
胎粪排出延迟与高胆红素血症有关。为了确定早期排出胎粪是否能有效降低血清总胆红素水平，84名足月健康新生儿被随机分为栓剂组或非栓剂组。通过过渡性粪便的出现来衡量，使用栓剂可使胎粪排出更早。然而，在出生后的头三天，对血清总胆红素水平没有显著影响。对于足月健康新生儿，不建议常规使用栓剂来降低血清总胆红素水平。
