Miller G, Heckmatt J Z, Dubowitz V
Arch Dis Child. 1983 Jun;58(6):445-50. doi: 10.1136/adc.58.6.445.
A series of 29 children with dermatomyositis has been reviewed and the outcome compared between cases treated by us initially with a low dosage short duration course of corticosteroids, and those referred late and having had various different therapeutic regimens and usually more active and higher dosage drug schedules. There were fewer relapses and less morbidity in the low dosage short term group. It was noted also that there was no relation between the initial mode of onset or severity and the eventual outcome or course of the disease. However, pronounced skin vasculitis appeared to reflect severity of disease.
回顾了29例皮肌炎患儿,比较了我们最初采用低剂量短疗程皮质类固醇治疗的病例与那些转诊较晚且接受过各种不同治疗方案、通常采用更积极且更高剂量用药方案的病例的预后。低剂量短期治疗组的复发较少,发病率也较低。还注意到疾病最初的发病方式或严重程度与最终预后或病程之间没有关联。然而,明显的皮肤血管炎似乎反映了疾病的严重程度。