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痛风患者及其家族中的血管性死亡率。

Vascular mortality in patients with gout and in their families.

作者信息

Darlington L G, Slack J, Scott J T

出版信息

Ann Rheum Dis. 1983 Jun;42(3):270-3. doi: 10.1136/ard.42.3.270.

Abstract

A mortality study was performed to determine death rates from coronary and cerebrovascular pathology in 180 patients with gout and their families. Lipid profiles were also analysed. Neither male nor female gout patients after presentation to hospital nor their male or female first-degree relatives were found to have an increased risk of dying from coronary artery or cerebrovascular disease. Families of hyperlipidaemic gout patients had a slightly increased incidence among males of death from coronary artery disease, a finding which may reflect the hypercholesterolaemia found among these relatives. It could have influenced the vascular mortality rate in families of hyperlipidaemic gout patients without any relationship to the diagnosis of gout itself.

摘要

开展了一项死亡率研究,以确定180名痛风患者及其家人因冠状动脉和脑血管病变导致的死亡率。还对血脂情况进行了分析。无论是入院后的男性还是女性痛风患者,以及他们的男性或女性一级亲属,均未发现死于冠状动脉疾病或脑血管疾病的风险增加。高脂血症痛风患者的家庭中,男性死于冠状动脉疾病的发生率略有增加,这一发现可能反映了这些亲属中存在的高胆固醇血症。它可能影响了高脂血症痛风患者家庭的血管死亡率,而与痛风本身的诊断并无任何关系。

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