痛风患者血脂和嘌呤水平的家族研究。
Family study of lipid and purine levels in gout patients.
作者信息
Darlington L G, Slack J, Scott J T
出版信息
Ann Rheum Dis. 1982 Jun;41(3):253-6. doi: 10.1136/ard.41.3.253.
Abstract
A family study was performed to determine whether the hypertriglyceridaemia associated with gout is present in families of gout patients or due to the life style of the patient himself. The study revealed the expected hypertriglyceridaemia in gout patients; this was reflected by elevated serum levels of prebetalipoproteins and with reduction in the proportion of beta-lipoprotein. None of these abnormalities were seen in the first-degree relatives. Furthermore, the proportion of high-density lipoproteins was not significantly raised in gout patients.
摘要
开展了一项家族研究，以确定与痛风相关的高甘油三酯血症是存在于痛风患者的家族中，还是由患者自身的生活方式所致。该研究发现痛风患者中存在预期的高甘油三酯血症；这表现为前β脂蛋白的血清水平升高以及β脂蛋白比例降低。在一级亲属中未观察到这些异常情况。此外，痛风患者中高密度脂蛋白的比例没有显著升高。
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