Wilson W J
Brain Res Bull. 1983 Apr;10(4):505-15. doi: 10.1016/0361-9230(83)90148-x.
A classical leg flexion conditioning paradigm was used to elicit specific motor responses, as well as nonspecific responses requiring less involvement of the motor system, in cats. Stimulating and lesioning the nucleus accumbens differentially affected these two types of responses. The specific conditioned responses, leg flexion and vocalization, were suppressed by stimulation and enhanced by lesions of the nucleus accumbens. The nonspecific responses, changes in respiration rate and amplitude, and in heart rate, were affected inconsistently or not at all. This suggests a role for the nucleus accumbens in the inhibition of motor components of learned emotional responses, and is consistent with hypotheses holding that the nucleus accumbens gates the access of the limbic system to motor systems.
在猫身上，采用经典的腿部屈曲条件反射范式来引发特定的运动反应以及运动系统参与度较低的非特异性反应。刺激和损伤伏隔核会对这两种类型的反应产生不同影响。特定的条件反应，即腿部屈曲和发声，会因伏隔核的刺激而受到抑制，因伏隔核的损伤而增强。非特异性反应，即呼吸频率和幅度以及心率的变化，受到的影响不一致或根本没有受到影响。这表明伏隔核在抑制习得性情绪反应的运动成分中发挥作用，并且与认为伏隔核控制边缘系统与运动系统联系的假说相一致。
