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吡罗昔康与吲哚美辛缓释剂治疗关节病的对比研究

[Comparative study of piroxicam and indomethacin retard in arthroses].

作者信息

Müller-Fassbender H, Nagel E

出版信息

Fortschr Med. 1981 Nov 26;99(44):1863-6.

PMID:7308953
Abstract

Indomethacin retard and piroxicam (Felden) were compared in an open, randomized parallel study in the treatment of osteoarthritis. Improvement of the symptoms of the disease was highly significant for both drugs. A statistical difference in the efficacy was not proved. Number and duration of the side effects were significantly lower with piroxicam than with indomethacin retard. Piroxicam was only applied once a day. Indomethacin retard was always (43% of the cases) or sometimes (14%) applied twice daily.

摘要

在一项治疗骨关节炎的开放性随机平行研究中,对消炎痛缓释剂和吡罗昔康(费啶)进行了比较。两种药物对疾病症状的改善均非常显著。未证实疗效上存在统计学差异。吡罗昔康的副作用数量和持续时间明显低于消炎痛缓释剂。吡罗昔康每日仅服用一次。消炎痛缓释剂总是(43%的病例)或有时(14%)每日服用两次。

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