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在人血清和呼吸道分泌物中肺炎支原体黏附蛋白抗体的检测

Demonstration of antibodies to Mycoplasma pneumoniae attachment protein in human sera and respiratory secretions.

作者信息

Hu P C, Huang C H, Collier A M, Clyde W A

出版信息

Infect Immun. 1983 Jul;41(1):437-9. doi: 10.1128/iai.41.1.437-439.1983.

DOI:10.1128/iai.41.1.437-439.1983
PMID:6862631
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC264800/
Abstract

Antibodies specific to the attachment protein of Mycoplasma pneumoniae were demonstrated in sera and respiratory secretions of human patients. The results indicate that the attachment protein is a major immunogen.

摘要

在人类患者的血清和呼吸道分泌物中证实了针对肺炎支原体黏附蛋白的特异性抗体。结果表明，该黏附蛋白是一种主要的免疫原。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1ef/264800/7a4ff20e6047/iai00136-0448-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1ef/264800/d94c6696d2bf/iai00136-0448-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1ef/264800/7a4ff20e6047/iai00136-0448-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1ef/264800/d94c6696d2bf/iai00136-0448-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1ef/264800/7a4ff20e6047/iai00136-0448-b.jpg

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Mycoplasma pneumoniae adhesin localized to tip structure by monoclonal antibody.肺炎支原体黏附素通过单克隆抗体定位于顶端结构。
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Molecular basis for cytadsorption of Mycoplasma pneumoniae.肺炎支原体细胞吸附的分子基础。
2008 年至 2009 年北京临床分离株肺炎支原体 p1 黏附素基因的序列分析。
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Identification of an N-terminal 27 kDa fragment of Mycoplasma pneumoniae P116 protein as specific immunogen in M. pneumoniae infections.鉴定肺炎支原体 P116 蛋白 N 端 27kDa 片段作为肺炎支原体感染的特异性免疫原。
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Strategy to create chimeric proteins derived from functional adhesin regions of Mycoplasma pneumoniae for vaccine development.用于疫苗开发的源自肺炎支原体功能性粘附素区域的嵌合蛋白构建策略。
Infect Immun. 2009 Nov;77(11):5007-15. doi: 10.1128/IAI.00268-09. Epub 2009 Aug 10.
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First report of macrolide-resistant strains and description of a novel nucleotide sequence variation in the P1 adhesin gene in Mycoplasma pneumoniae clinical strains isolated in France over 12 years.法国12年间分离的肺炎支原体临床菌株中耐大环内酯类菌株的首次报告及P1黏附素基因新核苷酸序列变异的描述
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