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放射性核素从血流中沉积在眼内可能产生的致白内障作用。

Possible cataractogenic effect of radionuclides deposited within the eye from the blood stream.

作者信息

Griffith T P, Pirie A, Vaughan J

出版信息

Br J Ophthalmol. 1985 Mar;69(3):219-27. doi: 10.1136/bjo.69.3.219.

DOI:10.1136/bjo.69.3.219
PMID:3978069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040567/
Abstract

The clinical and histological examination of a cataract in a man of 47 is described together with a review of the deposition of radionuclides in the eye. It is suggested that the cataract was possibly due, at least in part, to irradiation of the sensitive cells in the germinative zone of the lens epithelium by alpha particles deposited in the pigmented tissues of the eye from the 239Pu circulating in the blood.

摘要

本文描述了一名47岁男性白内障的临床和组织学检查情况，并对放射性核素在眼部的沉积进行了综述。研究表明，该白内障可能至少部分是由于血液中循环的239Pu在眼部色素组织中沉积的α粒子对晶状体上皮生发区敏感细胞的照射所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/7aeed93ad537/brjopthal00135-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/dfa409a00834/brjopthal00135-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/728f37b55b51/brjopthal00135-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/8cf35f4d17e5/brjopthal00135-0065-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/0f480387a3ee/brjopthal00135-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/243272ad3e48/brjopthal00135-0066-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/edd2d2f14157/brjopthal00135-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/78161c9d0165/brjopthal00135-0067-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/f2178e6db3c3/brjopthal00135-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/7aeed93ad537/brjopthal00135-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/dfa409a00834/brjopthal00135-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/728f37b55b51/brjopthal00135-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/8cf35f4d17e5/brjopthal00135-0065-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/0f480387a3ee/brjopthal00135-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/243272ad3e48/brjopthal00135-0066-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/edd2d2f14157/brjopthal00135-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/78161c9d0165/brjopthal00135-0067-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/f2178e6db3c3/brjopthal00135-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c896/1040567/7aeed93ad537/brjopthal00135-0069-a.jpg

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引用本文的文献

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本文引用的文献

1
Experimental studies on early lens changes after roentgen irradiation. III. Effect of x-radiation on mitotic activity and nuclear fragmentation of lens epithelium in normal and cysteine-treated rabbits.伦琴射线照射后晶状体早期变化的实验研究。III. X射线对正常及半胱氨酸处理家兔晶状体上皮细胞有丝分裂活性和核碎裂的影响。
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Clinical and pathological characteristics of radiation cataract.放射性白内障的临床及病理特征
AMA Arch Ophthalmol. 1952 Jan;47(1):55-70. doi: 10.1001/archopht.1952.01700030058006.
3
Experimental radiation cataracts. I. Cataracts in the rabbit following single x-ray exposure.
实验性辐射性白内障。I. 单次X射线照射后家兔的白内障
AMA Arch Ophthalmol. 1951 May;45(5):508-22.
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CATARACT EXTRACTION IN AN ENGLISH POPULATION.英国人群中的白内障摘除术
Br J Prev Soc Med. 1965 Apr;19(2):80-4. doi: 10.1136/jech.19.2.80.
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Differential distribution of radioactive strontium and yttrium in the tissues of the rabbit's eye.
Nature. 1959 Mar 21;183(4664):802-7. doi: 10.1038/183802a0.
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Barium and strontium concentrations in eye tissue.眼组织中的钡和锶浓度。
Biochem J. 1958 Dec;70(4):716-7. doi: 10.1042/bj0700716.
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Effects of high-energy particles, X-rays, and aging on lens epithelium.
AMA Arch Ophthalmol. 1955 Oct;54(4):489-514. doi: 10.1001/archopht.1955.00930020495003.
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The relationship of gamma and neutron radiation to posterior lenticular opacities among atomic bomb survivors in Hiroshima and Nagasaki.广岛和长崎原子弹爆炸幸存者中γ射线和中子辐射与晶状体后囊混浊的关系。
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Health Phys. 1983;44 Suppl 1:73-9. doi: 10.1097/00004032-198306001-00005.
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