Hedenstierna G, Järnberg P O, Torsell L, Gottlieb I
J Appl Physiol Respir Environ Exerc Physiol. 1983 May;54(5):1374-8. doi: 10.1152/jappl.1983.54.5.1374.
Esophageal elastance (Ees) was measured in 13 human subjects, awake and anesthetized by halothane, in the supine and left lateral postures. Static esophageal pressure was measured by an esophageal balloon catheter, respiratory volumes by pneumotachography, and functional residual capacity (FRC) by body plethysmography. In the supine awake subject, Ees averaged 3 cmH2O/ml at FRC and increased significantly with lung volume. Ees remained unaltered at FRC during anesthesia in the supine position, but lung volume dependence was no longer observed. In the left lateral position the awake subject displayed the same Ees at FRC as in the supine position and lung volume exerted only a small influence on Ees. The latter was reduced during anesthesia and tended to diminish with increasing lung volume. All variations in Ees caused by posture, anesthesia, and lung volume were small and affected the shape of the pressure-volume curve of the lung to only a minor degree.
在13名清醒及接受氟烷麻醉的人体受试者中，测量了仰卧位和左侧卧位时的食管弹性（Ees）。通过食管气囊导管测量静态食管压力，通过呼吸流速仪测量呼吸容积，通过体容积描记法测量功能残气量（FRC）。在清醒的仰卧位受试者中，FRC时Ees平均为3 cmH₂O/ml，并随肺容积显著增加。仰卧位麻醉期间，FRC时Ees保持不变，但不再观察到肺容积依赖性。在左侧卧位时，清醒受试者FRC时的Ees与仰卧位相同，肺容积对Ees的影响很小。麻醉期间Ees降低，并倾向于随肺容积增加而减小。姿势、麻醉和肺容积引起的Ees所有变化都很小，对肺压力-容积曲线形状的影响也很小。
