Narama I, Tsuchitani M, Umemura T, Tsuruta M
J Comp Pathol. 1983 Apr;93(2):195-203. doi: 10.1016/0021-9975(83)90006-3.
The histopathology of gastric papillomas in 17 crab-eating monkeys from Indonesia and Malaysia was investigated. The changes in the affected mucosa consisted of papillomatous proliferation with accidental heterotopia, desquamation or necrosis of the epithelium associated with eggs or adults of the small nematode Nochtia nochti, inflammatory cell infiltration and haemorrhage or oedema and fibrosis. The primary pathogenic effect of this parasite was due to its irritant action on the gastric mucosa. Hyper-regeneration, with a downward shift of the proliferating zone in the gastric gland and an inflammatory process, appeared to play a significant role in the morphogenesis of this lesion. It is concluded that the gastric papilloma associated with Nochtia nochti in the monkey is a parasitic inflammatory polyp.
对来自印度尼西亚和马来西亚的17只食蟹猴胃乳头状瘤的组织病理学进行了研究。受影响黏膜的变化包括乳头状增生伴偶发性异位、与小型线虫诺氏线虫的虫卵或成虫相关的上皮脱屑或坏死、炎性细胞浸润以及出血、水肿和纤维化。这种寄生虫的主要致病作用是因其对胃黏膜的刺激作用。胃腺中增殖区向下移位的过度再生以及炎症过程似乎在该病变的形态发生中起重要作用。结论是，猴体内与诺氏线虫相关的胃乳头状瘤是一种寄生性炎性息肉。
