Poiares Baptista A, Garcia E Silva L, Born M C
J Cutan Pathol. 1983 Jun;10(3):178-87. doi: 10.1111/j.1600-0560.1983.tb00324.x.
Fourteen cases (9 female, 5 male) of proliferating trichilemmal cysts are reported. The patients age-range was 40-80, 12 being over 60. The cysts wee present for 2-50 years and enlarged in the months or years before the observation. Seven were ulcerated. In 4 with multiple lesions both proliferating and ordinary trichilemmal cysts were present. The histological features were typical in all but one patient (evolution towards squamous cell carcinoma?) with some variation from lesion to lesion and from area to area in the same tumour. The microscopic features suggest that the proliferating trichilemmal cyst must be considered an hamartoma of the terminal hair follicle, not only related to the isthmic segment of the outer root sheath but with some differentiation (smaller and more variable) towards the infundibular and matricial segments. The tumour is likely to be a proliferating trichilemmal cyst from the beginning and not a peculiar evolution of an ordinary, pre-existant, trichilemmal cyst.
报告了14例增殖性外毛根鞘囊肿病例（9例女性，5例男性）。患者年龄范围为40 - 80岁，其中12例年龄超过60岁。囊肿存在2 - 50年，并在观察前数月或数年增大。7例发生溃疡。4例有多发性病变，同时存在增殖性和普通外毛根鞘囊肿。除1例患者（是否向鳞状细胞癌演变？）外，所有病例的组织学特征均典型，同一肿瘤的不同病变及不同区域存在一些差异。显微镜下特征表明，增殖性外毛根鞘囊肿必须被视为终末毛囊的错构瘤，不仅与外根鞘的峡部相关，而且对漏斗部和毛基质部分有一些分化（较小且更具变异性）。该肿瘤可能从一开始就是增殖性外毛根鞘囊肿，而非普通的、先前存在的外毛根鞘囊肿的特殊演变。
