Kronfol Z, Silva J, Greden J, Dembinski S, Gardner R, Carroll B
Life Sci. 1983 Jul 18;33(3):241-7. doi: 10.1016/0024-3205(83)90382-x.
Mood states and immunity may be related. To investigate the immune status of patients with primary depressive illness, we compared in-vitro lymphocytic responses to three different mitogens in 26 drug-free depressed patients and 20 normal controls of comparable age and sex. We observed a generalized and marked decrease in the lymphocyte mitogenic activity among the depressive group. This defect in lymphocyte function may be indicative of an impairment in cell-mediated immunity in patients with primary depressive illness.
情绪状态与免疫力可能相关。为研究原发性抑郁症患者的免疫状态，我们比较了26例未服用药物的抑郁症患者和20例年龄及性别相仿的正常对照者对三种不同有丝分裂原的体外淋巴细胞反应。我们观察到抑郁症组淋巴细胞有丝分裂活性普遍且显著降低。淋巴细胞功能的这一缺陷可能表明原发性抑郁症患者存在细胞介导免疫受损。
