Egami N, Shimada A, Hama-Furukawa A
Mutat Res. 1983 Feb;107(2):265-77. doi: 10.1016/0027-5107(83)90168-9.
When laying females or males of the small fish Oryzias latipes were irradiated with gamma-rays and then mated with a non-irradiated partner, the fertility and hatchability of the embryos were reduced as the doses increased. In respect to hatchability (the induction of dominant lethality), the male was more sensitive than the female, and mature sperm were most sensitive among the various stages of spermatogenetic cells. The dose-rate effects on the production of the dominant lethality were observed in spermatogonia and spermatocytes. The inbred strain of the fish, HB-1, was sensitive to gamma-rays. Since the relationship between dose and the decrease in hatchability was almost linear, at least within a limited range, we think that this system would be useful for monitoring mutagenic factors in an aquatic environment.
当用γ射线照射小型鱼类青鳉的雌鱼或雄鱼，然后与未受照射的配偶交配时，随着剂量增加，胚胎的受精率和孵化率会降低。就孵化率（显性致死的诱导）而言，雄性比雌性更敏感，并且成熟精子在生精细胞的各个阶段中最为敏感。在精原细胞和精母细胞中观察到剂量率对显性致死产生的影响。该鱼类的近交系HB-1对γ射线敏感。由于剂量与孵化率降低之间的关系几乎呈线性，至少在有限范围内是这样，我们认为该系统将有助于监测水生环境中的诱变因素。
