Flandrin J M, Courjon J H, Jeannerod M, Schmid R
Neuroscience. 1983 Apr;8(4):809-17. doi: 10.1016/0306-4522(83)90012-x.
Unilateral lesions of the cerebellar flocculus were performed in three chronically-implanted adult cats. Following the lesion a spontaneous nystagmus was observed in the dark, with the fast phase directed to the lesioned side. Vestibulo-ocular responses in the dark became asymmetrical. Responses to velocity steps exciting the labyrinth ipsilateral to the lesion were strongly increased. A decrease, although less marked, was observed in the opposite direction. Responses to sinusoidal oscillations in the dark were also asymmetric with respect to both the cumulative eye displacement during rotation in the two directions and the interval between two consecutive reversals of eye movement. These differences were greater at the lower tested frequencies (0.01 HZ) than at the higher (0.1 HZ). Spontaneous nystagmus disappeared in about 10 days and a complete symmetry of the vestibulo-ocular responses was restored in about 3 weeks. It is concluded that a unilateral lesion of the flocculus leads to two separate, but interacting, effects upon vestibulo-ocular responses.
对三只长期植入电极的成年猫进行了单侧小脑绒球损伤实验。损伤后，在黑暗中观察到自发性眼球震颤，快相指向损伤侧。黑暗中的前庭眼反射变得不对称。刺激损伤侧同侧迷路的速度阶跃反应显著增强。在相反方向观察到反应有所下降，尽管不太明显。黑暗中对正弦振荡的反应在两个方向旋转期间的累积眼位移以及眼动两次连续反转之间的间隔方面也不对称。这些差异在较低测试频率（0.01赫兹）时比在较高频率（0.1赫兹）时更大。自发性眼球震颤在大约10天内消失，前庭眼反射在大约3周内恢复完全对称。结论是，绒球单侧损伤会对前庭眼反射产生两种独立但相互作用的影响。
