• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

子宫内嗅觉功能的证据。

Evidence for olfactory function in utero.

作者信息

Pedersen P E, Stewart W B, Greer C A, Shepherd G M

出版信息

Science. 1983 Jul 29;221(4609):478-80. doi: 10.1126/science.6867725.

DOI:10.1126/science.6867725
PMID:6867725
Abstract

Pregnant rats received 2-[14C]deoxy-D-glucose (2DG) intravenously on the last day of gestation, and their fetuses were delivered 1 hour later by cesarean section. Fetal brains showed high 2DG uptake spread throughout the accessory olfactory bulb and little or no differential uptake in the main olfactory bulb. These findings demonstrate that functional activity occurs in the accessory olfactory bulb in utero and suggest that the accessory olfactory system may be the pathway by which fetal rats detect the odor quality of their intrauterine milieu.

摘要

妊娠大鼠在妊娠最后一天静脉注射2-[¹⁴C]脱氧-D-葡萄糖(2DG),1小时后通过剖宫产取出胎儿。胎儿大脑显示2DG摄取量高,分布于整个副嗅球,而主嗅球摄取量差异很小或无差异。这些发现表明,子宫内副嗅球存在功能活动,提示副嗅觉系统可能是胎鼠检测其子宫内环境气味质量的途径。

相似文献

1
Evidence for olfactory function in utero.子宫内嗅觉功能的证据。
Science. 1983 Jul 29;221(4609):478-80. doi: 10.1126/science.6867725.
2
One-trial olfactory learning enhances olfactory bulb responses to an appetitive conditioned odor in 7-day-old rats.单次嗅觉学习增强了7日龄大鼠嗅球对偏好性条件气味的反应。
Brain Res. 1987 Oct;432(2):307-11. doi: 10.1016/0165-3806(87)90056-3.
3
Early unilateral deprivation modifies olfactory bulb function.早期单侧剥夺会改变嗅球功能。
J Neurosci. 1990 Oct;10(10):3402-12. doi: 10.1523/JNEUROSCI.10-10-03402.1990.
4
Ontogenesis of the functional activity of rat olfactory bulb: autoradiographic study with the 2-deoxyglucose method.大鼠嗅球功能活动的个体发生:用2-脱氧葡萄糖法进行的放射自显影研究。
Brain Res. 1981 Sep;254(2):243-56. doi: 10.1016/0165-3806(81)90035-3.
5
Localized changes in olfactory bulb morphology associated with early olfactory learning.
J Comp Neurol. 1987 Sep 1;263(1):113-25. doi: 10.1002/cne.902630110.
6
Behavioral and neural correlates of postnatal olfactory conditioning: I. Effect of respiration on conditioned neural responses.出生后嗅觉条件反射的行为和神经关联:I. 呼吸对条件性神经反应的影响。
Physiol Behav. 1988;44(1):85-90. doi: 10.1016/0031-9384(88)90349-6.
7
Spatial patterns of olfactory bulb single-unit responses to learned olfactory cues in young rats.幼鼠嗅球对习得嗅觉线索的单单位反应的空间模式。
J Neurophysiol. 1988 Jun;59(6):1770-82. doi: 10.1152/jn.1988.59.6.1770.
8
Metabolic mapping of functional activity in the olfactory projections of the rat: ontogenetic study.
Brain Res. 1981 Aug;254(1):141-56. doi: 10.1016/0165-3806(81)90065-1.
9
Mapping of odor-related neuronal activity in the olfactory bulb by high-resolution 2-deoxyglucose autoradiography.通过高分辨率2-脱氧葡萄糖放射自显影术对嗅球中与气味相关的神经元活动进行映射。
Proc Natl Acad Sci U S A. 1982 Jan;79(2):670-4. doi: 10.1073/pnas.79.2.670.
10
Detection of propionic acid vapor by rats with lesions of olfactory bulb areas associated with high 2-DG uptake.
Brain Res. 1987 Aug 11;417(2):343-6. doi: 10.1016/0006-8993(87)90460-4.

引用本文的文献

1
Olfactory Development and Dysfunction: Involvement of Microglia.嗅觉发育与功能障碍:小胶质细胞的作用
Physiology (Bethesda). 2025 Mar 1;40(2):0. doi: 10.1152/physiol.00037.2024. Epub 2024 Nov 5.
2
Network Dynamics in the Developing Piriform Cortex of Unanesthetized Rats.未麻醉大鼠梨状皮层发育过程中的网络动态
Cereb Cortex. 2021 Jan 5;31(2):1334-1346. doi: 10.1093/cercor/bhaa300.
3
Diet-based assortative mating through sexual imprinting.通过性印记实现基于饮食的选型交配。
Ecol Evol. 2019 Sep 30;9(21):12045-12050. doi: 10.1002/ece3.5630. eCollection 2019 Nov.
4
Sensitive Periods, Vasotocin-Family Peptides, and the Evolution and Development of Social Behavior.敏感期、血管紧张素家族肽与社会行为的进化和发展
Front Endocrinol (Lausanne). 2017 Aug 2;8:189. doi: 10.3389/fendo.2017.00189. eCollection 2017.
5
Learned recognition of maternal signature odors mediates the first suckling episode in mice.学习识别母体气味介导了小鼠的第一次哺乳行为。
Curr Biol. 2012 Nov 6;22(21):1998-2007. doi: 10.1016/j.cub.2012.08.041. Epub 2012 Oct 4.
6
Chromosomal location-dependent nonstochastic onset of odor receptor expression.染色体位置依赖性气味受体表达的非随机起始。
J Neurosci. 2010 Jul 28;30(30):10067-75. doi: 10.1523/JNEUROSCI.1776-10.2010.
7
The rodent accessory olfactory system.啮齿动物的副嗅觉系统。
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2010 Oct;196(10):767-77. doi: 10.1007/s00359-010-0555-z. Epub 2010 Jul 4.
8
Morphogenesis and growth of the soft tissue and cartilage of the vomeronasal organ in pigs.猪犁鼻器软组织和软骨的形态发生与生长
J Anat. 2003 Jun;202(6):503-14. doi: 10.1046/j.1469-7580.2003.00183.x.
9
A genetic approach to trace neural circuits.一种追踪神经回路的遗传学方法。
Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3194-9. doi: 10.1073/pnas.96.6.3194.
10
Electron microscopic study of synaptogenesis and myelination of the olfactory centers in developing rats.
Exp Brain Res. 1995;103(3):385-92. doi: 10.1007/BF00241497.