Ogino H, Tada K, Okada K, Yonenobu K, Yamamoto T, Ono K, Namiki H
Spine (Phila Pa 1976). 1983 Jan-Feb;8(1):1-15. doi: 10.1097/00007632-198301000-00001.
Nine patients with cervical spondylotic myelopathy, diagnosed during life, were subjected to detailed clinicopathologic study. The degree of cord destruction was in good correlation with the ratio of the anteroposterior diameter to the transverse diameter, designated as an anteroposterior compression ratio. Within the factors responsible for decrease in the ratio, developmental narrowing of the spinal canal was the most significant, and multiplicity of spondylotic protrusion less so. The former resulted in an extensive demyelination of the posterolateral funiculus and infarction of the gray matter. Recurrent trauma proved to cause distinct manifestations and cord pathology. Clinicopathologic correlations were also examined from the neurologic findings at the terminal stage.
对9例生前诊断为脊髓型颈椎病的患者进行了详细的临床病理研究。脊髓破坏程度与前后径与横径之比(称为前后径压缩比)密切相关。在导致该比值降低的因素中,椎管发育性狭窄最为显著,而脊髓型突出的多发性则次之。前者导致后外侧索广泛脱髓鞘和灰质梗死。反复创伤被证明会导致明显的表现和脊髓病理改变。还从终末期的神经学表现检查了临床病理相关性。