Musella R, Giaccone G, D'Ambrosio E, Calciati A
Tumori. 1983 Jun 30;69(3):269-70. doi: 10.1177/030089168306900316.
A case of familial testicular malignancy in a father and his son is reported. This represents the seventh described case of father-son testicular cancer. The father had seminoma and the son had teratocarcinoma. Both patients' peripheral blood lymphocytes were tested for 52 HLA specificities: the father's antigens were HLA A3, B13, B14, Cw6, Cw8 and the son's were HLA A2, A3, B14, Cw8. (Common haplotype: A3, B14, Cw8). The association between HLA antigens and testicular cancer is discussed.
报告了一例父亲和儿子患家族性睾丸恶性肿瘤的病例。这是所描述的第七例父子患睾丸癌的病例。父亲患精原细胞瘤，儿子患畸胎癌。对两位患者的外周血淋巴细胞进行了52种HLA特异性检测：父亲的抗原为HLA A3、B13、B14、Cw6、Cw8，儿子的抗原为HLA A2、A3、B14、Cw8。（共同单倍型：A3、B14、Cw8）。讨论了HLA抗原与睾丸癌之间的关联。
