Melamed I, Bujanover Y, Igra Y S, Schwartz D, Zakuth V, Spirer Z
Am J Dis Child. 1983 Aug;137(8):752-3. doi: 10.1001/archpedi.1983.02140340036009.
Campylobacter fetus subspecies jejuni (CBJ) has been recently recognized as a common pathogen in bacterial gastroenteritis in children. During a period of 16 months, 51 cases of C fetus subspecies jejuni gastroenteritis were diagnosed. Five of the children in whom the cases were diagnosed were previously known to be immunodeficient: two had X-linked agammaglobulinemia, one had agammaglobulinemia, one had combined immunodeficiency, and one had transient hypogammaglobulinemia. Average duration of fever and diarrhea was longer in the five immunodeficient children (15 and 23 days, respectively) compared with the normal children (four and five days, respectively). Excretion of C fetus subspecies jejuni in stool persisted for 20 to 27 days in four of the immunodeficient children and for one year in the fifth, whereas normal children excreted C fetus subspecies jejuni for only four to 16 days. Campylobacter fetus subspecies jejuni may be added to the list of bacterial pathogens most likely to infect immunodeficient children, especially those with a defect of the humoral system.
胎儿弯曲菌空肠亚种（CBJ）最近被认为是儿童细菌性肠胃炎的常见病原体。在16个月的时间里，共诊断出51例胎儿弯曲菌空肠亚种肠胃炎病例。确诊病例中的5名儿童之前已知存在免疫缺陷：2名患有X连锁无丙种球蛋白血症，1名患有无丙种球蛋白血症，1名患有联合免疫缺陷，1名患有暂时性低丙种球蛋白血症。与正常儿童（分别为4天和5天）相比，这5名免疫缺陷儿童的平均发热和腹泻持续时间更长（分别为15天和23天）。4名免疫缺陷儿童粪便中胎儿弯曲菌空肠亚种的排泄持续了20至27天，第5名儿童则持续了1年，而正常儿童排出胎儿弯曲菌空肠亚种的时间仅为4至16天。胎儿弯曲菌空肠亚种可能会被添加到最有可能感染免疫缺陷儿童的细菌病原体名单中，尤其是那些体液系统有缺陷的儿童。
