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东京一所幼儿园发生空肠弯曲菌胎儿亚种所致急性肠炎疫情。

An outbreak of acute enteritis due to Campylobacter fetus subspecies jejuni at a nursery school of Tokyo.

作者信息

Itoh T, Saito K, Maruyama T, Sakai S, Ohashi M, Oka A

出版信息

Microbiol Immunol. 1980;24(5):371-9. doi: 10.1111/j.1348-0421.1980.tb02841.x.

Abstract

An outbreak of acute enteritis due to Campylobacter fetus subspecies jejuni involving a total of 35 out of 74 children occurred at a nursery school of Tokyo in January 1979 and lasted for 7 days. It was the first case of a community outbreak of the disease to be recognized in Japan. The major symptoms observed in the patients consisted of diarrhea (88%), fever (82%), abdominal pain (39%), and vomiting (6.1%). The rate of isolation of the organism from the patients was 39%. Sera of four patients showed elevated agglutinin titers against the organism ranging from 1:80 to 1:320. Although it is suggested that the outbreak was caused by a communal lunch or between-meal snacks prepared by and provided at the nursery school, the incriminated food, source and route of contamination could not be pinpointed.

摘要

1979年1月,东京一所幼儿园爆发了由空肠弯曲菌胎儿亚种引起的急性肠炎,74名儿童中有35人感染,疫情持续了7天。这是日本首次确认的该疾病社区爆发病例。患者观察到的主要症状包括腹泻(88%)、发烧(82%)、腹痛(39%)和呕吐(6.1%)。从患者中分离出该病菌的比例为39%。4名患者的血清显示针对该病菌的凝集素效价升高,范围从1:80到1:320。尽管有人认为此次疫情是由幼儿园准备和提供的集体午餐或课间零食引起的,但无法确定罪魁祸首食物、污染源和污染途径。

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