Lambe D W, Ferguson D A, Wiener S L, Butzler J P
South Med J. 1981 Feb;74(2):157-61. doi: 10.1097/00007611-198102000-00008.
Within a seven-month period, Campylobacter fetus ssp jejuni was isolated in East Tennessee from 18 patients with gastroenteritis; 83% of these patients had bloody diarrhea. Absence of other enteric organisms such as Salmonella, Shigella, and Yersinia implicated C fetus ssp jejuni as the causative agent. A fourfold increase in titer by tube agglutination from four of eight patients studied supported the pathogenicity of this organism. Treatment with erythromycin alleviated gastroenteritis symptoms within 24 to 48 hours, with concurrent disappearance of the organism from the feces. An isolation rate of 8% in our patients indicates that C fetus ssp jejuni is more common as a cause of human diarrhea than Salmonella or Shigella. The severity of the C fetus ssp jejuni gastroenteritis poses a possible reclassification from diarrhea or gastroenteritis to acute dysentery syndrome.
在七个月的时间里，在田纳西州东部从18例肠胃炎患者中分离出空肠弯曲菌胎儿亚种；这些患者中有83%出现血性腹泻。未发现其他肠道病原体，如沙门氏菌、志贺氏菌和耶尔森氏菌，这表明空肠弯曲菌胎儿亚种是病原体。在接受研究的8名患者中，有4名患者的试管凝集效价增加了四倍，这支持了该病原体的致病性。用红霉素治疗可在24至48小时内缓解肠胃炎症状，同时该病原体从粪便中消失。我们患者中的分离率为8%，这表明空肠弯曲菌胎儿亚种作为人类腹泻的病因比沙门氏菌或志贺氏菌更常见。空肠弯曲菌胎儿亚种肠胃炎的严重程度可能导致从腹泻或肠胃炎重新分类为急性痢疾综合征。
