Lebrun L, Tram C, Lapierre F, Grangeot-Keros L, Pillot J
Ann Microbiol (Paris). 1983 Mar-Apr;134A(2):155-61.
Guinea-pigs were experimentally infected with Legionella pneumophila. L. pneumophila antigen was detected in urine samples by a double antibody sandwich ELISA. Urinary antigen was present from the beginning of the acute phase of the disease. In two out of five cases, this antigen was found with no antibody detectable in sera by indirect immunofluorescence staining.
豚鼠通过实验感染嗜肺军团菌。采用双抗体夹心酶联免疫吸附测定法（ELISA）检测尿样中的嗜肺军团菌抗原。在疾病急性期开始时即可检测到尿抗原。在五例病例中有两例，通过间接免疫荧光染色在血清中未检测到抗体，但却发现了这种抗原。
